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Supplements With Metformin: What to Ask Before You Add Drops
Taking supplements with metformin is a decision for your doctor or pharmacist, not a label. Some ingredients may add to diabetes drugs. Payarmin lists chromium, gymnema and ginseng among 23 lines, and no study of the product exists. Keep taking metformin as prescribed.
Written by the Payarmin daily deskUpdated · 4 min read
Can you take supplements with metformin?
Only your doctor or pharmacist can say for your case. Supplements can interact with prescription drugs, and a label cannot know your dose or your other medicines (NCCIH, Using Dietary Supplements Wisely).
The American Diabetes Association advises discussing any supplement with your care team first (ADA, Vitamins & Supplements). It does not recommend any supplement for glucose control.
Never stop or change metformin, or any other prescription, because of a supplement. Payarmin is not a replacement for it.
Which supplement ingredients may add to diabetes drugs?
Chromium is the best documented. It may add to the effect of insulin and other diabetes drugs, which raises the chance of low blood sugar (NIH ODS, Chromium).
Payarmin has 0.7 mcg of chromium, tiny next to the hundreds of mcg in trials. The blend adds more lines to check.
| Line | Why it comes up |
|---|---|
| Chromium, 0.7 mcg | May add to diabetes drugs (NIH ODS, Chromium) |
| Gymnema, 8th of 22 | Studied for glucose; at most 25 mg here (Drugs.com, Gymnema monograph) |
| Panax ginseng, 12th | Small drop in fasting glucose in trials (Shishtar et al., PLoS One 2014) |
| African mango, 4th | Caution with diabetes drugs (MSKCC, Irvingia gabonensis (African mango)) |
What if blood sugar drops while you take both?
Know the signs of a low, and act on them. For many people with diabetes a low is under 70 mg/dL (NIDDK, Low Blood Glucose).
The drugs the source names for causing lows are insulin, sulfonylureas and meglitinides. Ask which class your prescriptions fall in.
- Shaky or jitteryTrembling hands, feeling nervous
- Tired or irritableSudden tiredness or a short temper
- Hungry, nauseousSudden strong hunger
- Dizzy, confusedTrouble thinking or speaking clearly
- Fast heartbeatPounding or racing pulse
15-15For many people with diabetes, a low is under 70 mg/dL. Take 15-20 g of fast carbohydrate (juice, glucose tablets), then check again in 15 minutes.
Call 911When someone with a low passes out, has a seizure or cannot swallow safely. Never give food or drink to someone who is unconscious.
Signs and steps are from NIDDK (NIDDK, Low Blood Glucose). Lows can come from insulin, sulfonylureas and meglitinides, and supplements may add to them (ADA, Vitamins & Supplements).
Payarmin: from $49 a bottle30 mL · 2, 3 or 6 bottles · free US shipping on 3 and 6 · 60-day results-or-refund guarantee
See packsWhat should you bring to the pharmacist?
Bring the bottle, the 23 label lines and your medicine list. A pharmacist can check each line against each prescription.
The label
Show the Supplement Facts panel, since the amounts are hidden.
The directions
1 or 2 droppers a day; the dropper volume is not printed.
Your meter log
Readings from before and after you start.
The label also tells people with a known medical condition to ask a physician first. More at supplements and diabetes medicines.
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FAQ01
More about metformin and supplements
Does Payarmin interact with metformin?
No interaction study of Payarmin is named, so we cannot say. Chromium, gymnema and ginseng may add to diabetes drugs, so ask your pharmacist to check the label against your list before you start.
Is it safe to take chromium with metformin?
Ask your pharmacist. Chromium may add to the effect of diabetes drugs and raise the chance of lows (NIH ODS, Chromium). Payarmin has only 0.7 mcg, but doses in chromium-only products run from 200 to 500 mcg.
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Pages built from the label, the sales page and linked NIH, FDA, CDC, FTC and peer-reviewed sources.
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